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Background: Zingiber officinale (Zingiberaceae) has been utilized to remedy many afflictions of humans Literary works illustrate that it possesses numerous biological activities Methods: Today, research study intended to recognize the Phyto-derived anti-viral substances from Zingiber officinale against COVID-19 main protease enzyme and to understand the molecular basis of its activity Methods: In the present study, 42 molecules obtained from Z officinale, which are retrieved from the Pubmed database, are studied via docking study Docking study was performed using Autodock vina and PyRx software Afterwards, admet SAR, as well as Dru Li to servers, were made use of for drug-likeness prophecy Results: Our study shows that the nine phytochemicals of Z officinale are very likely against the main protease enzyme of COVID-19 Utilizing contemporary strategies, these phyto-compounds might use to establish a reliable medication from a natural origin Conclusion: The substances identified potential as possible anti-virals However, even more, in-vitro studies are needed to examine their effectiveness versus COVID-19

In-silico Strategies of Some Selected Phytoconstituents from Zingiber officinale as SARS CoV-2 Main Protease (COVID-19) Inhibitors