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Maize Hm1 gene encodes a NAD(P)H-dependent HC-toxin reductase, which detoxify HC-toxin produced by fungus Cochliobolus carbonum (Meeley and Walton 1991 Plant Phys 97: 1080). Measurements of ion leakage indicated that H2O2 treatment of a recessive mutant (hm1) of maize resulted in accelerated death in excised leaves. Furthermore, an hm1 maize showed quantitative decrease of NAD(H) level. Thus, the Hm1 gene may confer other functions related to ROS stress tolerance.

Maize plants mutated in NAD(P)H-dependent HC-toxin reductase gene (Hm1) is vulnerable to H2O2 stress