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Cholecystokinin receptor subtype 2 (CCK-2) is overexpressed in various tumours like medullary thyroid carcinomas and small cell lung cancer. Radiolabelled peptides that bind with high affinity and specificity to CCK-2 receptors, thus hold great potential for visualizing such tumours.

biomedical papers/biomedical papers of the faculty of medicine of palacký university, olomouc czech republic

Preclinical evaluation of gastrin derivatives labelled with &lt;sup&gt;111&lt;/sup&gt;In: Radiolabelling, affinity profile and pharmacokinetics in rats