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Very modest changes in mRNA stability can affect critical points in cellular energy pathways. The aim of this study was to investigate the impact of energy abundant substrates on peroxisome proliferator-activated receptors (PPARs) and PPAR-gamma coactivators (PGCs) mRNA's steady-state levels.

biomedical papers/biomedical papers of the faculty of medicine of palacký university, olomouc czech republic

mRNA LEVELS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS AND THEIR COACTIVATORS ARE AFFECTED BY GLUCOSE DEPRIVATION AND OLEATE IN HUMAN HEPATOMA HepG2 CELLS