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The increase in maternal age in recent years has intensified the effort to develop early non-invasive methods for screening for trisomy 21 and other chromosomal abnormalities in prenatal diagnosis. In the first trimester of pregnancy, maternal age, fetal nuchal translucency (NT), maternal levels of free beta- human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A) are used as screening markers. We evaluated the introduction of this method of screening for the first time in the Czech Republic.

biomedical papers/biomedical papers of the faculty of medicine of palacký university, olomouc czech republic

SCREENING FOR CHROMOSOMAL ANOMALIES IN THE FIRST TRIMESTER: A REPORT ON THE FIRST YEAR OF PROSPECTIVE SCREENING FOR CHROMOSOMAL ANOMALIES IN THE FIRST TRIMESTER IN THE CZECH REPUBLIC