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Metallothioneins belong to the group of intracellular, high molecular and cysteine-rich proteins whose content increase with increasing concentration of a heavy metal. Here we applied the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothionein in human blood serum of patient poisoned by lead and/or treated by platinum. The increased metallothionein concentrations in both cases were observed.

biomedical papers/biomedical papers of the faculty of medicine of palacký university, olomouc czech republic

USING OF ELECTROCHEMICAL METHODS FOR STUDYING OF METALLOTHIONEIN CONTENT IN THE HUMAN BLOOD SERUM OF A PATIENT POISONED BY LEAD AND TREATED BY PLATINUM