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Background: Scientific literature suggests that different types of training can have different effects on secretion of irisin and myostatin. Objectives: The purpose of this study was to determine the effect of resistance exercise training (RET), aerobic exercise training (AET) and concurrent (aerobic + resistance) exercise training (CET) on serum irisin and myostatin in untrained women. Methods: Thirty-five non-obese, untrained women were randomly assigned to control (n = 6, age 25.50 +/- 4.80 years), RET (n = 10, age 24.60 +/- 2.45 years), AET (n = 9, age 24.66 +/- 2.29 years) or CET (n = 10, age 26.60 +/- 4.00 years) groups. Subjects in training groups trained for 8 weeks, three times per week. The levels of serum irisin, myostatin were measured before and after the training period. Results: It was found that the CET group had significantly reduced serum irisin (p = .028) and myostatin (p = .005) concentrations. The myostatin concentration was also significantly decreased in the RET group (p = .008). Conclusion: CET, AET or RET were not effective for improving (increase) irisin circulating level. In addition, RET and CET were more effective than AET in reducing circulating myostatin levels.

Effects of aerobic training, resistance training, or both on circulating irisin and myostatin in untrained women