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Gülnur Taşçı Bozbaş Yazışma Adresi: Physical Medicine and Rehabilitation Department, Adnan Menderes University Medical School, Aydın. e-mail: gulnurtb@yahoo.com Abstract Purpose: Rheumatoid arthritis (RA) is a disease that characterized by joint damage including periarticular osteoporosis and focal bone erosion. Despite the fact that periarticular osteoporosis and erosions are known as radiographic hallmarks of RA, there is a lack of data on the relationship between forearm bone loss and radiographic damage. For this reason, we aimed in this study to determine whether there is a relationship between focal erosions and OP in RA patients. Materials and methods: We evaluated 49 female patients with RA. Anteroposterior hand and foot radiographs and bone mineral density measurement of forearm, hip and lumbar spine with dual x-ray absorptiometry of all patients were taken at simultaneously. Radiographs were analyzed using the Larsen method. Disease activity was evaluated by DAS-28 and functional ability was measured with Health Assessment Questionnaire and Duruöz Hand Index. Results:Patients had the mean age 53.9±11.8 and an average disease duration of 7.9±5.9 years. The erosion score was correlated with bone mineral density of forearm, but not with lumbar spine and hip. The disease activity and functional ability were not correlated with Larsen score. Both osteoporosis in all evaluated area and correlations were not affected by the menopause status and disease duration. Conclusion: Our results demonstrated that bone mineral density of forearm indicate the erosion severity in female patients with RA.

The relation between joint erosion and forearm bone mineral density in female patients with Rheumatoid Arthritis