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Aim: Iron deficiency anemia (IDA) is one of the most important health problems in both fertile women and children living in developing countries. This condition must be treated quickly and safely. The present study aimed to compare the efficacies of intravenous ferrous carboxymaltose treatment and oral iron treatment in reproductive-aged women with IDA. Material and Method: This retrospective study included 202 reproductive-aged women who were diagnosed as IDA with a hemoglobin level of <11 g/dL. Patients were divided into two groups to be administered a single dose of 1000 mg intravenous ferric carboxymaltose (n=112) and 325 mg/day oral ferrous sulphate (n=90) for four weeks. All the anemia parameters of the patients were compared before and after treatment. Results: There were significant increases in hemoglobin concentration, ferritin values, and transferrin saturation levels after treatment in both groups. However, the increases in these values were significantly higher in the group receiving ferric carboxymaltose (p<0.001). There was no significant difference in the side effects between the group receiving ferric carboxymaltose and the group receiving oral ferrous sulphate (6.7% vs. 8.9%, p=0.554). Conclusion: Ferric carboxymaltose treatment could be used effectively and reliably in patients who could not tolerate oral iron treatment.

Comparison of Ferric Carboxymaltose and Oral Iron Treatments in Iron Deficiency Anemia