English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Our aim is to determine treatment response to Cyberknife based on follow-up MRI in patients with pituitary adenoma. METHODS: We retrospectively identified the patients with pituitary adenoma treated with Cyberknife between 2010 – 2014. Patients with postreatment eligible follow-up MRI scan after at least 6 months of Cyberknife treatment were included in this study. Preand posttreatment MRI scans of 38 patients (male/female=1) were retrospectively analysed to evaluate tumor response. Volumetric changes of the tumors, local control rate, volumetric changes over time and signal alterations on the surrounding brain parenchyma were assessed. RESULTS: The mean follow-up time of 38 patients was 25 months (range, 6-51 months). Significant mean tumor volume reduction was found between preand posttreatment mean tumor volumes, which were 4722 mm3 and 3475 mm3, respectively. There were 2 cases with radiological progression, 18 cases with stable disease and 18 cases with regression. Thus, tumor local control rate was calculated as 94.7% in our study. There was also a significant follow-up time difference between stable and radiological regression groups which indicates that increased follow-up time may be related with better volume decrease. Patient gender, additional medical treatment, age, the number of previous surgeries did not affect treatment response. Lastly, there was no case with signal alteration on the surrounding brain parenchyma.

Cyberknife Radiotherapy for Pituitary Adenomas: Monitoring Response Using Magnetic Resonance Imaging