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In this case report tumor control was evaluated with only radiotherapy without surgery in the management of recurrent liposarcoma. Recurrent mass on the left posterior thigh was developed in 40 years old woman whom surgery was performed without adjuvant chemotherapy for an initial stage of T2bN0M0 well-differentiated liposarcoma, 5 years after surgery. Magnetic resonance imaging (MRI) showed signs of recurrent mass (38x32x15mm) in initial location. The patient was referred to our center for radiotherapy, since she did not accept surgery. We performed fractioned stereotactic radiotherapy (FSRT) with CyberKnife® (Accuray Inc., Sunnyvale, CA), for recurrent tumor and external beam radiation therapy (EBRT) for the microscopic tumor around the recurring mass. At 49 months follow-up MRI showed down sizing of tumor by 40 %. FSRT and/or EBRT may be a promising in terms of treatment alternative but this should be confirmed by more studies

Management of Recurrent Liposarcoma with Fractionated Stereotactic Radiotherapy: A Case Report