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Supplementary Table 1. Summary of top three tier pediatric UTI CPGs recommendations* (lifted statements as per each guideline statements) Spain NICE AAP Year 2011 2007 2011 Scope and objectives To improve clinical management of children with UTI Aim of this guideline is to achieve more consistent clinical practice, based on accurate diagnosis and effective management of UTI in children... To revise the AAP practice parameter regarding the diagnosis and management of initial UTIs in febrile infants and young children Target population: Children from 1 month to 18 years old with suspected UTI ...on the care of infants, children and young people younger than 16 years with UTI... Focuses on the diagnosis and management of initial UTIs in febrile infants and young children (2–24 months of age) who have no obvious neurologic or anatomic abnormalities known to be associated with recurrent UTI or renal damage Intended for health professionals in primary care and specialist care ...all healthcare professionals involved in providing care for children who have a UTI (including GPs, nurses, pediatricians, nephrologists and urologists) those responsible for commissioning and planning healthcare services, including primary care trust commissioners, Health Commission Wales commissioners, and public health and trust managers c) children who have UTI and their families Intended for use in a variety of clinical settings (e.g., office, emergency department, or hospital) by clinicians who treat infants and young children

Supplementary data: A critical review of recent clinical practice guidelines for pediatric urinary tract infection