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Crohn’s disease is a lifelong chronic relapsing transmural inflammatory bowel disease most commonly known to affect any portion of the gastrointestinal tract from the mouth to the anus in a skip-lesion fashion. Typical presentation occurs in patients between the ages of 15‒30 with fever, abdominal pain, weight loss, and bloody or non-bloody diarrhea.1 In pediatric patients, it may present with growth impairment, failure to thrive, and delayed puberty.2 Common extraintestinal or metastatic manifestations of Crohn’s disease include uveitis, erythema nodosum, and arthritis. Currently, there are few reports of urogenital metastatic Crohn’s disease in the pediatric population. Children who present in the absence of any gastrointestinal symptoms often have difficulties in receiving the correct diagnosis, leading to delayed and/or inappropriate management. The fact that persistent penile swelling is an uncommon pediatric condition, along with its many different etiologies, means it can be difficult for a patient who first presents to be correctly diagnosed with metastatic Crohn’s disease of the genitourinary tract. Increased awareness and reporting of this rare condition can help improve timely diagnosis and appropriate, evidencebased treatment for these patients.

Case: Metastatic Crohn’s disease of the genitalia in a prepubescent male: An illustrative case of an uncommon diagnosis