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Background: The association between Helicobacter pylori (HP) infection and dyspeptic symptoms has long been established with HP infection having a 5% population attributable risk for dyspepsia. Aim: Using a near- patient testing method, this study determined the prevalence of Helicobacter pylori infection, assessed sociodemographic influence on Helicobacter pylori infection and determined the treatment outcome of the subjects. Design: A prospective study Setting: The study was carried out at the family medicine clinic of the University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria. Methods. Consenting and eligible dyspeptic patients were tested for Helicobacter pylori using 14Carbon Urea Breath Test (CUBT). CUBT-positive patients had eradication therapy for Helicobacter pylori, while CUBT-negative patients had empirical therapy. Follow –up period was 8 to 12 weeks. Result. The prevalence of dyspepsia at the University of Port Harcourt Teaching Hospital Family Medicine Clinic was 6%. The mean age of respondents was 38.7±14.5 years. The prevalence of Helicobacter pylori infection in this study was 44.7% with a cure rate of 81.1% using recommended eradication regime. This study also showed a statistically significant relationship between the social class and age of the subjects and Helicobacter pylori infection, with lower socioeconomic class and increasing age being more infected with HP. Conclusion. Primary care management of Helicobacter pylori infection using the near- patient testing approach with good patient outcome can reduce burden on specialist consultation and secondary care facilities.

Prevalence of Helicobacter pylori-related dyspepsia using a near-patient testing method in Port Harcourt, Nigeria.