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Background: Animals eat to acquire the energy and building materials that they need to live and grow the nutrient required to achieve such, abound in phyto-materials. The synergistic, additive, or complementary immuno-modulatory effects of phytocomponents from A. senegalensis and Alium cepa were evaluated in this work. Methods: Seventy indigenously developed varieties of day-old broilers were divided in a completely randomized design(CRD) into 5 (n=14) treatment groups (T1-T5) treatments with 2 replicates per treatment. At the finisher level, 0.0, 0.2, 0.3, 0.4, and 0.5 kg of the A. senegalensis-garlic (ASG) cocktail was added to the normal finisher diet. Results: Feed consumption tends to increase significantly (p≤0.05) with the increased level of ASG Cocktail. values recorded 1405±17.9 g, 1450±21.5 g, 1310±20.6 g, 1450±17.3 g, 1340±15.3g for T1, T2, T3, T4, and T5 respectively were recorded. There is a significant difference (p≤0.05) in the total protein (TP) at different inclusion levels with 0.5% having the highest value of 57.95±4.07 g/dl. The triglycerides and cholesterol levels decrease as the ASG inclusion level increases which shows the anticholesteremic potency of the blend. There are significant increases (p≤0.05) in the albumin and globulin concentrations as the level of ASG inclusion increased. However, while there is a significant increase (p≤0.05) in the aspartate transaminase along the concentration gradient, the reverse is the case with regards to alanine transaminase. A significant decrease (p≤0.05) in bilirubin concentration along the inclusion gradient (except in T5). There was a significant increase (p≤0.05) in body weight across the inclusion gradient except in T3. The Feed Conversion Ratio (FCR) follows a regular pattern with a range of 0.51-0.53 except for the birds fed with 0.3% inclusion (T3) that recorded a higher (poor) value of 0.89. Conclusion: Supplementation with ASG cocktail improves the performance and the immune-competence of the bird at the finisher stage

Performance and serum biochemistry of broiler chickens fed diet supplemented with Annona senegalensis-Garlic Cocktail