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Com o objetivo de avaliar os efeitos da solucao contendo acidos graxos essenciais, lecitina de soja e vitaminas A e E sobre a cicatrizacao secundaria de feridas dermoepidermicas, observou-se a evolucao da reparacao tecidual em nove caes machos, SRD, com idade variando entre tres e cinco anos e peso de 12 kg em media. Para isto, em cada paciente foram produzidos dois defeitos de pele, medindo 6cm de altura (sentido dorsoventral) x 4cm de largura (sentido craniocaudal) em ambas as faces laterais do torax e do abdome, sendo que nas lesoes do lado esquerdo procedeu-se a avaliacao fisica e mensuracao diaria, enquanto que nas feridas do lado direito, realizou-se biopsia incisional a cada dois dias. Nas lesoes abdominais esquerdas, tratadas com acidos graxos e curativos umidos com solucao fisiologica 0,9%, tanto macro como microscopicamente, observou-se inflamacao aguda durante os tres primeiros dias, sendo esta seguida pelos eventos de granulacao, contracao e reepitelizacao completa ate o 25o dia. Nas feridas toracicas esquerdas, expostas ao iodo polivinilpirrolidona e curativos umidos, constatouse a predominância dos eventos inflamatorios agudos por sete dias, seguida dos fenomenos proliferativos, de contracao e completa reepitelizacao ate o 31o dia pos cirurgico. A ausencia de sinais compativeis com toxicidade sistemica e a mais rapida cicatrizacao das lesoes tratadas com acidos graxos, permitem a indicacao desta solucao para o tratamento de feridas abertas dermoepidermicas, em caes. Secondary cicatrization in dermoepidermal wounds treated with essential fatty acids, vitamins A and E, soy lecithin and polynylpyrrolidone-iodine in dogs Abstract The effects of a solution containing essential fatty acids, soy lecithin and vitamins A and E in the healing of canine second intention dermoepidermal wounds were evaluated. In order to observe evolution of the tissue repair. Nine male, mixed breed dogs, with age varying between three and five years and average weight of 12 kg, were used in the experiment. Skin wounds were surgically performed in each dog. Two defects (6 x 4 cm) were performed in both thoracic and abdominal lateral faces of the animals. Daily physical evaluation and measurement were analyzed in the lesions situated on the left side, while incisional biopsy every other day was performed in the right side lesions. The left abdominal lesions, treated with fatty acids and humid curatives with physiologic solution 0.9 %, showed macro and microscopic changes such as acute inflammation during the firs three days. After this period and until the 25th day, granulation tissue followed by contraction events and total reepitelization were observed. The left thoracic lesions, treated with povidone-iodine and humid curatives, showed predominance of acute inflammatory events during the first seven days; these events were followed by proliferative and contraction events and by the total recovery of the epithelial surface until the 31st day after the surgery. In conclusion, the absence of compatible signs with systemic toxicity and the fastest healing of the lesions treated with fatty acids allow its indication for dermoepidermal wound treatment in dogs.

archives of veterinary science

CICATRIZAÇÃO SECUNDÁRIA EM FERIDAS DERMOEPIDÉRMICAS TRATADAS COM ÁCIDOS GRAXOS ESSENCIAIS, VITAMINAS A e E, LECITINA DE SOJA E IODO POLIVINILPIRROLIDONA EM CÃES