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TEPC (Tissue Equivalent Proportional Counter) was usually used for high LET radiation dosimetry. We developed a prototype TEPCfor micro-dosimetry in the range of 0.2~300 keV/µm. And, the simulated site diameter of the TEPC is 2µm, of similar size to a cellnucleus. For purposes of characterization the response for high LET radiation of the TEPC has been investigated under 135 MeV/u Car-bon ions in HIMAC (Heavy Ion Medical Accelerator). We determined the gas multiplication factor and measured the lineal energy s pec-trum [yd(y)] of 135 MeV/u Carbon ions. The value of the gas multiplication factor was 315 at 700 V bias voltage. As a result of theexperiment, we could more understand the performance of the TEPC for high LET (Linear Energy Transfer) radiation. And the pro-cedure of high LET radiation dosimetry using TEPC is established.Keywords: Equivalent dose, TEPC, LET, Lineal energy, Micro-dosimetry, Site diameter 1.           (high linear energy transfer; LET)   ,        [1,2],            [3,4]. ,            , (tissue equivalent proportional counter; TEPC) (micro-dosimetry)   [5],     [6,7]. Fig. 1       .    40 mm,  30 mm A-150( 10.2%,  77.6%,  5.2%)  ,   C

Measurement of Linear Energy Spectra for 135 MeV/u Carbon Beams in HIMAC Using Prototype TEPC