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Serotonergic drugs have been used for the treatment of various psychiatric disorders such as anxiety disorders, impulse control disorders and especially depression. Gastrointestinal system symptoms, weight changes and sleep disturbances are commonly observed side effects of serotonergic drugs. Drug-induced movement disorders are classically associated with dopamine receptor blocking agents, most notably typical and atypical antipsychotic medications. However, extrapyramidal side effects can also be seen with serotonergic agents, antiemetics, and opioid agonists. The most common extrapyramidal system symptoms are akathisia, dystonia, parkinsonism, and tardive dyskinesia. We describe a patient who developed an acute dystonic reaction after taking 100 mg trazodone and his symptoms resolved after receiving intra muscular anticholinergic treatment.

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