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Synchronous carcinomas are defined multiple primary neoplasms occurring in different locations belonging to different morphologic or histologic origin ocurrin at the same time in a patient. This is the first report of a cutaneous squamous cell carcinoma presenting synchronically with a clear renal cell carcinoma, confirming is not a metastatic process. Case Report: A 53-year-old man had a clinical course of eight months of evolution, of a continuously growing mass in the left gluteus and thigh with inguinal adenopathies, in the same place of a previously burn area, for which complementary imaging studies were indicated to establish the extent of the lesion, with an incidental finding of a tumor in left kidney. Biopsies of the gluteal and left kidney lesions were performed, showing a verrucous variant squamous cell carcinoma in gluteal region and a clear cell differentiation concordant with clear cell renal cell carcinoma in left kidney. Conclusion: Synchronous carcinoma implies a complex interactions between genetic and environmental factors for its development. Clinical manifestations usually presents in advance stages of both carcinomas, but can be detected with extension studies as in this case.

Synchronous carcinomas of primary origin: Squamous cell carcinoma of the skin and clear cell renal cell carcinoma