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The study aimed to identify bioactive compounds in  Muntingia calabura  leaf and root methanolic extracts. The Gas Chromatography and Mass Spectroscopy (GC-MS) technique were used to identify bioactive compounds. GC-MS analysis revealed 38 compounds in the leaf and 15 compounds in the root methanolic extracts of  M. calabura . The prime potent compound found in leaf extract is 2-{3-[(E)-2-(1H-indol-3-yl)ethenyl]-1,2,4-oxadiazol-5-yl}phenol with 5.78% peak area and cholest-4-en-6-on-3-ol is found in root extracts, has the highest 63.7% peak area and another potent compound Lupeol has 7.3% peak area. The bioactive compounds identified in  M. calabura  have antibacterial activity against various bacterial strains such as gram-positive and gram-negative bacteria, which showed the efficacy of  in vivo  plant extracts. These findings validate the therapeutic potentiality of  M. calabura  leaf and root samples. Furthermore, these screened potential bioactive compounds can be used effectively for biomedical and therapeutic applications.

natural resources for human health

Gas Chromatographic analysis of potentially bioactive compounds in leaf and root extracts of &lt;i&gt;Muntingia calabura&lt;/i&gt; and their expected antibacterial activities