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ABS TRACT Objective: Early detecting acute renal failure is important by the aspect of determination of the disease's severity and grade of the organ dysfunction. The Acute Dialysis Quality Initiative workgroup designed a classification system for acute kidney injury (AKI) named as the RIFLE (Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease). The aim of our study is to assess acute renal failure development in intensive care units patients, factors affecting it and the effect of the factors over mortality via using RIFLE score. Material and Methods: The age, height, weight, gender, diagnosis, comorbid diseases, admission reason to the intensive care, intensive care stay, the APACHE II score, SOFA score, RIFLE score, biochemical parameters (albumin, prealbumin, urea, creatinine, cholesterol, HCO3 level), triceps thickness and waist circumference measurement were all recorded. Patients were grouped into AKI and non-AKI. The AKI group was assessed by RIFLE score due to hourly urine output and creatinine rise separated into three groups as R=Risk, I=Injury, F=Failure. Results: 502 patients were enrolled to the study. 39,2% of the patients was in the acute kidney injury group while 60.8% was in nonacute kidney injury group. The renal failure development is related with high age, short body height, excessive weight, existence of chronic disease and long intensive care units hospitalization period. Conclusion: In conclusion, patients with high age, excessive weight, chronic diseases, high urea, creatinine, HCO3levels, low cholesterol, albumine and prealbumine levels are prone to renal failure.

Factors Affecting Acute Renal Failure in Intensive Care Unit and Effect of These Factors on Mortality