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ABS TRACT Ob jec ti ve: To in ves ti ga te the ef fects of tam su lo sin (α-1 ad re ner gic re cep tor an ta go nist) on the ma in nu me ri cal pa ra me ters of an te ri or seg ment using Pen ta cam ro ta ting Sche immp flug ca me ra, and on bi o mec ha ni cal pa ra me ters using Re ic hert Ocu lar Res pon se Analy ser (ORA) in pa ti ents with be nign pros ta te hyperp la si a. Ma te ri al and Met hods: In ad di ti on to full eye exa mi na ti on [best cor rec ted vi su al acu ity, ke ra to metry, in tra o cu lar pres su re (IOP) me a su red with Gold mann app la na ti on to no metry], Pen ta cam [cen tral cor ne al thick ness (CCT), an te ri or cham ber depth, ante ri or cham ber vo lu me, an te ri or cham ber ang le, pu pil di a me ter] and ORA (cor ne al hyste re sis, cor ne al re sis tan ce fac tor, cor ne al com pen sa ted IOP, Gold mann cor re la ted IOP) me a su re ments of 30 eyes of 15 ma le pa ti ents we re per for med be fo re and one month af ter tam su lo sin the rapy. Pa i red ttest and non-pa ra met ric Wil co xon test we re used for com pa ri sons. Re sults: Me an age in the study gro up was 61.50±6.10 (ran ge 47-69) ye ars. Af ter tam su lo sin tre at ment, CCT in cre a sed and this incre ment was sta tis ti cally sig ni fi cant (p=0.002). No ne of the ot her pa ra me ters that we re eva lu a ted sho wed sta tis ti cally sig ni fi cant dif fe ren ce af ter tam su lo sin use. Conc lu si on: Tam su lo sin le ads to signi fi cant in cre ment in CCT. The ef fects of tam su lo sin on CCT sho uld be ta ken in to con si de ra ti on for pro per cli ni cal in ter pre ta ti on in pa ti ents using tam su lo sin.

Influence of Tamsulosin on the Anterior Segment Parameters and Central Corneal Thickness