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ABS TRACT Ob jec ti ve: Left ven tri cu lar re mo de ling ac ce le ra tes the co ur se of car di ac fa i lu re by aggra va ting ven tri cu lar dysfunc ti on fol lo wing myo car di al in farc ti on. Thus, pre dic ti on and pre ven ti on of left ven tri cu lar re mo de ling is cru ci al. The aim of this study was to eva lu a te the pre dic ti ve va lu e of pe ri o pe ra ti ve plas ma NT-proBNP le vels for pos to pe ra ti ve left ven tri cu lar re ver se re mo de ling and ejec ti on frac ti on in pa ti ents who un der went co ro nary ar tery bypass graf ting. Ma te ri al and Met hods: Forty pa ti ents with myo car di al in farc ti on inprevious thre e months we re en rol led in the study. All pa ti ents with mo de ra te left ven tri cu lar dysfunc ti on (EF ≤40%) un der went on pump co ro nary ar tery bypass graf ting (CABG) ope ra ti on. Pa ti ents’ pre o pe ra ti ve left ven tric le vo lu mes and in de xes, ejec ti on frac ti ons, and NT-proBNP le vels we re com pa red to the pos to pe ra ti ve va lu es. Results: Pre o pe ra ti ve NT-proBNP le vels we re sig ni fi cantly re la ted to pre o pe ra ti ve and pos to pe ra ti ve ejec ti on frac ti ons, and pos to pe ra ti ve left ven tri cu lar re ver se re mo de ling (p= 0.037, p= 0.033, p= 0.014, res pec ti vely). Conc lu si on: The pre o pe ra ti ve N-ter mi nal proBNP may help to as sess the pos to pe ra ti ve ejec ti on frac ti on and ven tri cu lar re mo de ling. Ami no ter mi nal proBNP is a sa fe, ava i lab le and ef fec ti ve to ol to pre dict the pos to pe ra ti ve func ti o nal and struc tu ral chan ges of the left ven tric le.

türkiye klinikleri tıp bilimleri dergisi

Amino Terminal Pro-B-Type Natriuretic Peptide and Late Left Ventricular Reverse Remodeling in Coronary Artery Bypass Grafting Patients with Low Ejection Fraction