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a potentially life-threatening form of hypersensitivity condition triggered by exposure to certain drugs, commonly aromatic anticonvulsant, sulpha derivates, antidepressants, nonsteroidal anti-inflammatory drugs, and certain antimicrobials.1 Rarely it can be triggered by anti-tuberculosis medication as observed in the patient reported in this article. DRESS syndrome is characterized by fever, maculopapular skin rash, lymphadenopathy, haematological abnormalities such as thrombocytopenia, eosinophilia and lymphocytosis, and variable internal organ involvement such as liver, kidney, heart and lungs. The onset is typically between 2 to 8 weeks after drug exposure. The mainstay of treatment is prompt identification of the signs and symptoms, rapid withdrawal of the offending drug, and commencement of systemic steroids if indicated in severe cases. DRESS syndrome has a mortality rate up to 10 to 20%. Therefore, it is imperative to avoid diagnostic delay as it can cause detrimental consequences to the patient.

A Rare, Fatal But Treatable Anti-tuberculosis Drug Reaction: A Case Report on DRESS Syndrome Secondary to Akurit-4