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Background: Globally prostate cancer is the sixth leading cause of cancer-related deathin men. Prostate Specific Antigen (PSA) is present in small amount in the serum of menwith healthy prostates, but is often elevated in the presence of prostate cancer and otherprostate-related disorders. The aim of this present study was to determine the PSA levelsamong healthy men of African descent resident in Sokoto, North Western Nigeria.Methods: Testing was carried out using the CTK Biotech PSA kit (CTK Biotech Inc, SanDiego, USA). The Onsite PSA Rapid Test is a lateral flow chromatographic immunoassayfor the qualitative detection of prostate specific antigen (PSA) in human serum or plasmaat a cut-off level of 4.0 ng/mL.Result: We investigated the PSA levels in 106 consecutively recruited men of Africandescent with age range and mean age of 40-70 years and 44.75 ± 7.91 yearsrespectively. We observed a PSA of > 4ng/mL among 7 (6.6%) of subjects studied. Men >60 had the highest prevalence of raised PSA level (33.3%) compared to those youngermen (p= 0.001). We observed a higher prevalence among farmers (11.1%) compared tobusiness men, civil servants and students.Conclusion: In this present study we observed a high prevalence of PSA >4ng/mL and apositive and significant correlation between age and raised PSA levels among men inSokoto, North Western Nigeria. We recommend an annual PSA blood test for men ≥ 40years of age and that those with a PSA value > 4.0 ng/mL should be considered forfurther evaluation. There is also the need to build capacity among biomedical and medicalstaff in Nigeria to facilitate effective diagnosis of prostate cancer. There is also the needfor increased prostate cancer awareness in the area to facilitate voluntary testing

Prostate Specific Antigen (PSA) Screening among Apparently Healthy Men of African Descent in Sokoto, North Western, Nigeria