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Two copper (II) complexes, [Cu(B)(L-Ser)TU]ClO4 (B=1,10- phenanthroline (phen) in complex 1, and 2,2’-bypyridine (bpy) in complex 2, L-Ser =L-Serine,TU= thiourea), have been synthesized and characterized by Infra-red, EPR spectral and elemental analysis methods. The one-electron paramagnetic complexes display a d–d band near 600 nm in water. Binding modes of the complexes with calf-thymus DNA have been studied by electronic absorption spectroscopy, emission spectroscopy, viscosity and cyclic voltammetry.  We continued to study the cytotoxicity activity of complex 1 by using HepG2 cells. Further complex 1 & 2 were tested for their antimicrobial activities and it was found to have good antimicrobial activities

SYNTHESIS, CHARACTERIZATION, DNA BINDING/CLEAVAGE STUDIES AND BIOLOGICAL AND ANTICANCER ACTIVITY OF COPPER (II) COMPLEXES