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Acitretin is retinoic acid derivative that is approved for treatment of severe psoriasis. The side effect of retinoic therapy is all-trans retinoic acid syndrome. Here, we report a case of acitretin treatment associated acute lung injury in a psoriasis patient. Exhibited as a diffuse lung parenchymal injury, the differential diagnosis of infection, heart failure, and alveolar hemorrhage should be ruled out. A definite medication history is prerequisite for diagnosis of the disease. After correct diagnosis, the patient responded well to corticosteroid and the symptom and radiological changes of acitretin-induced acute lung injury alleviated soon.

Responding well to corticosteroid in an acitretin treatmentRelated acute lung injury patient with psoriasis