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Germinomas are the most frequent type of germ cell tumors that constitute only 2-5% of all central nervous system malignancies. Most of them arise in the pineal and suprasellar regions but in about 5% to 10% the simulta- neous location is found. Although their strategic location, they respond well to surgery, radiation and chemotherapy and the prognosis is very good. We report a case of 23- years young male presented with gait disturbance, weak- ness in lower extremities, visual impairment and moder- ate fatigue. His medical history revealed that he was symptomatic by DI (polyuria, polydypsia and weight loss) and received treatment with adiuretin for a period of 3 years. Computed tomography (CT) scans demonstrated well circumscribed tumor lesions with a homogeneous contrast enhancement in the suprasellar and pineal regions. A germinoma was verified histologically. A good treatment response to surgery, radiation, chemotherapy and management of endocrine insufficiency was achieved. The postoperative neurological, CT and immunological follow-up corresponded with the clinical course of the disease and the results of therapeutic procedures.

CNS GERMINOMA WITH SYNCHRONOUS LESIONS IN THE SUPRASELLAR AND PINEAL REGIONS: CLINICAL, CT AND IMMUNOLOGICAL FOLLOW-UP