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This experiment was undertaken to investigate the hypocholesterolemic effect of prepared soy milk (PSM). Experiment l In order to study the effect of three,different oils(soybean, corn, sunflower oil)and soybean-phospholipids (soybean-lecithin:LEC) on serum cholesterol (CHOL), rats were fed a hypercholesterolemic diets for two weeks. The values of serum CHOL in rats fed sunflower oil, corn oil and soybean oil were 166 mg/dl,175 mg/dl and 227 mg%dl respectively. These values were lower than that(275 mg/dl)in rats fed casein-lard diet. The values of serum CHOL in rats fed O%soybean-LEC(corn oil group), 0.3%soybean-LEC and 3%soybean-LEC diets were 175 mg/dl,186 mg/dl and 160 mg/dl respectively. Experiment 2 1n order to examine the CHOL-lowering effect of PSM and milk on hypothyroid hypercholesterolemia induced by 2-thiouracil(TU), rats were fed a diet with or without O.3/TU for three weeks. The values of serum CHOL in rats fed PSM, PSM-TU, milk or milk-TU were 67 mg/dl,119 mg/dl, 70mg/dl and 128 mg/dl respectively. These results suggest that prepared soy milk is capable of alleviating exogenous hypercholesterolemia, but not of improving endogenous hypercholesterolemia.

Effect of Prepared Soy Milk on Dietary or Hypothyroid Hypercholesterolemia in Rats.