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Ultrasonography (US) findings and Doppler sonography of renal vessels can provide useful information on the structural and vascular supply of patients suffering from chronic kidney disease (CKD). The purpose of this study was to compare the US findings of patients with diabetic nephropathy with the pathologic findings of their renal biopsy. In this descriptive study, US parameters including resistivity index (RI), renal size and volume and cortical and medullary echogenicity, and histopathological findings of renal biopsy (fibrosis, inflammation and chronicity) of 60 patients (27 women and 33 men) with diabetic nephropathy admitted in Hasheminejad kidney center (HKC) of Tehran were extracted and analyzed. Of 60 patients, interstitial fibrosis (IF) in 47 patients, interstitial inflammation (II) in 50 patients and signs of chronicity in 43 patients in pathology report were observed. Patients with IF had larger renal length, higher sinus volume, coarse echogenicity, and abnormal medullary echogenicity, significantly. The presence of II was associated with larger renal length, higher renal and sinus volume, higher cortical echogenicity, and more patients with coarse echogenicity and abnormal medullary echogenicity. The observation of chronicity was significantly correlated with higher sinus volume and more patients with irregular renal rim. According to the findings of this study, renal length and volume, renal sinus volume, and the presence of coarse echogenicity and abnormal medullar echogenicity strongly correlate with renal histopathologic findings in patients with diabetic nephropathy. RI is not a suitable marker for identifying tubulointerstitial changes in these patients.

periódico tchê química

ARE PATIENTS WITH DIABETIC NEPHROPATHY DIFFERENT REGARDING RENAL ULTRASOUND PARAMETERS AND DOPPLER SONOGRAPHY FINDINGS COMPARED WITH RENAL HISTOPATHOLOGY?