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The peculiarities of pituitary- thyroid regulation of the protein metabolism in the replacement gilts of different bred and the correlations between the hormone levels and the blood parameters and economically beneficial features were studied. The test groups were formed based on the results of the assessment that was performed when the gilts gained 100.00 ± 10.00 kg of live weight. The first group included Duroc animals (n=30), the second group – Yorkshire animals (n=90) and the third group – Landrace animals (n=15). The study was conducted by biotechnological, biochemical and statistical research methods. It was proved that Duroc,Yorkshire and Landrace gilts T3 and TSH levels were not significantly different, their hormone concentration varied within the range of 7.60±0.12 – 8.61±0.28 pmol/L and 0.02±0.001 – 0.03±0.004 μIU/ml, respectively. T4levels in Landrace gilts were higher than in analogs by 27.41 and 28.91% (р≤0.05). The rate of thyroid hormone bioconversion (Т3/Т4) was evaluated by the ratio of TSH/Т3, TSH/Т4,and TSH/Т3+Т4. The concentration of total protein, albumins, globulins, and Alb/Gl-coefficient varied within the range of 63.73±0.72 – 65.99±0.51, 28.56±0.34 –29.23±0.67, 34.47±1.12 – 37.43±0.61 g/L and 0.76±0.02 –0.86±0.04 SU, respectively, and did not depend on the breed. Significant correlations were revealed in Durocs between Т3 – urine (r= –0.42±0.15; р≤0.05) and TSH - absolute weight gain, weaning time (r=0.52±0.13; р≤0.05); in Yorkshires, Т3 – total protein (r= –0.31±0.10) and T4 - absolute weight gain, weaning time (r=0.51±0.08; р≤0.05); in Landraces, Т4 – total protein (r= – 0.68±0.14; р≤0.05) and T4 - assessment age (r=0.66±0.15; р≤0.05).

THYROID HORMONE ROLE IN METABOLIC STATUS AND ECONOMIC BENEFICIAL FEATURES FORMATION IN REPLACEMENT GILTS OF DIFFERENT BREEDS