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favorable malignant diseases globally. In the Republic of Belarus, it ranks third (8.2%) in the cancer incidence structure and&#x0D;first (21.5%) in the cancer mortality structure.&#x0D;The object of the study were the lung cancer incidence and&#x0D;mortality trends in the Republic of Kazakhstan in 1990-2019.&#x0D;Methods: The present study included all patients - residents of Belarus, registered in the national cancer registry from&#x0D;1990 to 2019 with a diagnosis of lung cancer (ICD-10 code:&#x0D;C33-C34). Demographic variables included gender, age, and&#x0D;area of residence (urban or rural). The number of PD cases is&#x0D;presented as absolute values and rough intensity indicators&#x0D;per 100,000 population. Standardized morbidity and mortality&#x0D;rates are calculated using the world standard (World) and are&#x0D;indicated per 100,000 population.&#x0D;Results: In the study period, the standardized incidence&#x0D;rate decreased from 27.5 to 25.6 per 100 000 population&#x0D;(– 7.1%, p&lt;0.01). In males, it decreased from 62.1 to 54.6 per 100&#x0D;000 males (– 12.1%, p&lt;0.001); in females, it increased from 5.3&#x0D;to 6.4 per 100 000 females (+20.7%, p&lt;0.05).&#x0D;The standardized lung cancer mortality rate has decreased&#x0D;over the study period from 23.0 to 18.3 per 100 000 population&#x0D;(– 20.4%, p&lt;0.001). In males, it went down from 53.6 to 40.7 (–&#x0D;24.1%, p&lt;0.001), and in women it changed slightly from 3.6 to&#x0D;3.7 (+2.8%, p&gt;0.05) per 100 000 of the relevant sex. The average annual increase in standardized mortality decreased eight&#x0D;times faster than the growth in standardized incidence.&#x0D;Conclusion: In the Republic of Belarus, lung cancer incidence is increasing in males and decreasing in females. At that,&#x0D;lung cancer mortality is decreasing. Quality specialized cancer&#x0D;care creates conditions for quicker negative growth of lung cancer standardized mortality vs. incidence

Lung cancer incidence and mortality trends in the Republic of Belarus (1990-2019)