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Quercetin is a flavonol present at high levels in onions, apples, tea and red wine. Although quercetin has been epidemiologically associated with bioactive protective effects, this compound has also been shown to be mutagenic and toxic in short-term in vitro test systems. This study evaluated quercetin for toxicity in the MCF-7 cell line in the presence or absence of benzo[a]pyrene (B[a]P), a known DNA-reactive carcinogen. In the clonogenic assay, 2.5 × 10 2

Dose-related effects of Quercetin in the human breast carcinoma MCF-7 cell line