English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Monocrotophos is an organophosphate pesticide used in agriculture to control a range of insect pests. The aim of this study was to investigate the sub-lethal toxicity of the pesticide at different concentrations on rat liver. Experimental animals were chronically exposed to different concentrations of monocrotophos (0.625, 1.25, 2.5, 5.0 and 10.0 ml/kg body weight/day p.o.) for 14 days. The control rats were placed on borehole water devoid of pesticide. The toxic potential was evaluated using transaminases as bio-markers. Oral administration of the pesticide significantly increased the hepatosomatic index of the animals when compared with the control after 14 days of treatment. A significant reduction was also observed in the activities of aspartate transaminase (AST) and alanine transaminase (ALT) in the liver, which were significantly increased in the serum in a concentration dependent manner following ingestion of the pesticide. The findings from the present study showed that exposure to monocrotophos may compromise normal functioning of the liver.

Monocrotophos–induced enzymatic changes as toxicity bio-markers in Wistar Rat liver