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Tuberculosis (TB) continues to be a devastating disease worldwide in the 21 Century and it is believed that one third of the World’s populations are infected. 22 Countries are responsible for over 80% of the global TB burden, Nigeria is rank 4and have the highest burden in Africa. A number of anti tuberculosis drugs are ineffective against this disease due to the emergence of resistance strains. As part of the effort in developing a new anti tuberculosis agent, we decided to interact with traditional medicine practitioners of the Plateau region on their approach to the management of TB. A total of fourteen (14) plants representing nine families were identified as the most often used plants to manage TB symptoms in the region. The plants materials were extracted using 70% aq. methanol and the extracts obtained after concentration were screened against BCG. The results of the assay showed that 56% of the plants screened had MICs within the range of 800μg/ml to 2000μg/ml and as such had antimycobacterial activity. These plants are potential sources for herbal drugs for exhibiting these strong inhibitory properties and could also provide leads to tuberculosis drug development.

Antimycobacterial evaluation of some medicinal plants used in plateau State of Nigeria for the treatment of tuberculosis