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A 22-year-old Japanese man visited our hospital with a large tumor on his occipital region. He first noted a nodule on his scalp when he was 14-years-old in 1986. Although the tumor was excised in 1987, he noticed recurrence one year later. Since then, surgical excision of recurrent tumors had been performed six times. In 1994, he complained of frequent headaches, walking disturbance and visual disorder. Physical examination revealed several large nodules located on the anterior border of the previously grafted skin. Magnetic resonance imaging showed the scalp mass invading the cerebral parenchyma. The recurrent tumors were further resected five times. In spite of the radiotherapy and chemotherapy, the tumor progressively disseminated into spinal cord, and he died of respiratory failure in January, 2000. [Skin Cancer (Japan) 2001; 16: 77-82]

A Case of Recurrent Dermatofibrosarcoma Protuberans Invading the Cerebral Parenchyma.