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Transient Myeloproliferative Disorder (TMD), is an important hematological disorder which is seen in newborns with Down syndrome. It is often self-limiting and spontaneous remissions occur within 3 months. Leukocytosis, thrombocytopenia, anemia, hepatosplenomegaly, the presence of cutaneous nodules and blasts in the peripheral blood are characteristic findings. We present a TMD case of newborn with Down syndrome and aimed to emphasize the importance of early diagnosis and therapy of these patients.

When should transient myeloproliferative disorder of the newborn with Down syndrome be treated? Case report