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This paper proposes, designs and demonstrates experimentally a tapered fibre optic biosensor (TFOBS) fabricated by an optically controlled HF chemical etching. The fabricated device is demonstrated to operate properly as a label-free sensor for glucose concentration detection. This work presents a novel fabrication method of a single-mode TFOBS controlling the reaction rate by changing the HF concentration and monitoring the optical power variation at the fibre output. Two TFOBS fabricated with different cladding diameters are evaluated experimentally to sense different glucose concentrations observing the changes in the refractive index of the medium in various solvents. The sensing capabilities are evaluated by modal interferometry measurement of both intensity and phase variations of the received optical signal.

Tapered Fibre Optic Biosensor (TFOBS) by Optically Controlled Etching for Label-Free Glucose Concentration Monitoring - Biomedical Optics