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The treatment of HeLa neoplastic cells with low frequency and intensity electromagnetic field has determined modifications of the micronuclei number, this impact being correlated with the application manner of the electromagnetic field (continuous or discontinuous). Thus, the continuous electromagnetic field has reduced the frequency of the micronuclei formation (2.91 ± 0.015 ‰), as compared to the value of control group (3.93 ± 0.023 ‰), while the discontinuously applied electromagnetic field has increased the number of micronuclei (4.92± 0.012 ‰). These variations in micronuclei number has suggested that low frequency electromagnetic field interfere in different ways with the genetic material of cancerous cells, indicating that the cEMF had a protective effect upon DNA molecule, while dcEMF had a genotoxic impact. Also, the estimation of the micronuclei area has revealed that the area of micronuclei generated by dcEMF was smaller than that of cEMF.

THE CONSEQUENCES OF LOW FREQUENCY AND INTENSITY ELECTROMAGNETIC FIELDS ON THE FREQUENCY OF MICRONUCLEI IN HeLa CELLS