Candida albicans E Candida tropicalis ISOLADAS DE ONICOMICOSE EM PACIENTE HIV-POSITIVO: CO-RESISTÊNCIA IN VITRO AOS AZÓLICOS

The present study analyzes a case of onychomycosis by Candida species with resistance “in vitro” to fluconazole and itraconazole in a patient infected by the human immunodeficiency virus (HIV). The patient presented partial dystrophic onychomycosis with chronic paronychia and previous use of fluconazole for treatment of oral candidiasis. Scales scraped from the fingernails demonstrated hyaline yeasts with blastoconidia and pseudohyphae; and in culture, after growth: two species of Candida that have been identified as Candida tropicalis and Candida albicans. Antifungal susceptibility tests with 2 ATB® FUNGUS and method of Disc diffusion for fluconazole were carried out. Both species presented resistance to fluconazole and itraconazole. The peculiarities of the various species of Candida justify the need to identify yeast species, as well as the sensitivity profile to antifungal agents in clinical use, to better therapeutic and minimize the exposure of these patients to fungal dissemination.