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The PubMed Clinical Study Category filters are subdivided into "Broad" and "Narrow" versions that are designed to maximize either sensitivity or specificity by using two different sets of keywords and Medical Subject Headings (MeSH). A searcher might assume that all items retrieved by Narrow would also be found by Broad, but there are occasions when some [Filter name] /Narrow citations are missed when using [Filter name] /Broad alone. This study quantifies the size of this effect.

Mind the gap: identifying what is missed when searching only the broad scope with clinical queries