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The validation of ozone profiles retrieved by satellite instruments throughcomparison with data from ground-based instruments is important to monitorthe evolution of the satellite instrument, to assist algorithm developmentand to allow multi-mission trend analyses.  In this study we compare ozone profiles derived from GOMOS night-timeobservations with measurements from lidar, microwave radiometer and balloonsonde. Collocated pairs are analysed for dependence on several geophysicaland instrument observational parameters. Validation results are presentedfor the operational ESA level 2 data (GOMOS version 5.00) obtained duringnearly seven years of observations and a comparison using a smaller datasetfrom the previous processor (version 4.02) is also included.  The profiles obtained from dark limb measurements (solar zenith angle>107°) when the provided processing flag is properly considered matchthe ground-based measurements within ±2 percent over the altitude range20 to 40 km. Outside this range, the pairs start to deviate more and thereis a latitudinal dependence: in the polar region where there is a higheramount of straylight contamination, differences start to occur lower in themesosphere than in the tropics, whereas for the lower part of thestratosphere the opposite happens: the profiles in the tropics reach lessfar down as the signal reduces faster because of the higher altitude atwhich the maximum ozone concentration is found compared to the mid and polarlatitudes. Also the bias is shifting from mostly negative in the polarregion to more positive in the tropics  Profiles measured under "twilight" conditions are often matching theground-based measurements very well, but care has to be taken in all caseswhen dealing with "straylight" contaminated profiles.  For the selection criteria applied here (data within 800 km, 3 degrees inequivalent latitude, 20 h (5 h above 50 km) and a relative ozoneerror in the GOMOS data of 20% or less), no dependence was found onstellar magnitude, star temperature, nor the azimuth angle of the line ofsight. No evidence of a temporal trend was seen either in the bias orfrequency of outliers, but a comparison applying less strict data selectioncriteria might show differently

GOMOS ozone profile validation using ground-based and balloon sonde measurements