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Variation in  KRTAP6-1  has been reported to affect wool fibre traits in Merino cross-breed sheep and Chinese Tan sheep, but little is known about whether these effects persist in other breeds. In this study, variation in  KRTAP6-1  was investigated in 290 New Zealand (NZ) Romney ewes sired by 16 different rams. Polymerase chain reaction single-stranded conformational polymorphism (PCR-SSCP) analysis revealed four variants (   A   ,    B   ,    E    andF  )of  KRTAP6-1 , and nine genotypes ( AA ,  AB ,  AE ,  AF ,  BB ,  BE ,  BF ,  EE  and  FF ) in these ewes. Among the 243 ewes that had genotypes with a frequency of over 5 % (i.e.  AA ,  AB  and  BB ), the presence of    A    was found to be associated with reduced mean fibre diameter (MFD) and increased coefficient of variation in fibre diameter (CVFD), whereas the presence of    B    had a trend of association with decreased coarse edge measurement (CEM). A genotype effect was also detected for MFD and CVFD. No associations were detected for fibre diameter standard deviation (FDSD), mean fibre curvature (MFC) and medulation. These results suggest that variation in  KRTAP6-1  affects wool fibre diameter in NZ Romney ewes, confirming the finding in Merino cross-breed sheep.

Variation in &lt;i&gt;KRTAP6-1&lt;/i&gt; affects wool fibre diameter in New Zealand Romney ewes

Variation in <i>KRTAP6-1</i> affects wool fibre diameter in New Zealand Romney ewes