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The hypocretin receptor1 (HCRTR1) gene encodes a Orexin A receptor(SAKURAI et al., 1998). It belongs to the class Ι subfamily within the superfamily ofG-coupled receptors and is coupled to Ca2+ mobilization. Via HCRTR1, Orexin A isinvolved in the control of feeding, sleep-wakefulness, neuroendocrine homeostasis andautonomic regulation (VOISIN et al., 2003; TAKESHI SAKURAI, 1999). Thesecharacters are important in animal production. In human, a 408 isoleucine to valinemutation in HCRTR1 showed significant association with polydipsic–hyponatremicschizophrenia (MEERABUX et al., 2005). By now, no polymorphisms of the bovineHCRTR1 gene were reported

archives animal breeding/archiv für tierzucht

Eleven single nucleotide polymorphisms (SNPs) were found at coding region of hypocretin receptor1 (&amp;lt;i&amp;gt;HCRTR1&amp;lt;/i&amp;gt;) gene in cattle (Brief report)