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The aim of our studies was to determine, whether difference in GH alleles affect growth Performance in cowsand whether these effects may be mediated by IGF-I. The presence of L (leucine-rich) and V (valine-rich) allelesof GH, plasma IGF-I level and changes in body mass were analyzed in 84 bulls of Simmental (meat) andHolstein (milk) breeds at 90 d and 180 d of age using PCR, agarose gel electrophoresis and IRMA The agedependentincrease in body mass, daily gain and plasma IGF-I concentration was observed in Simmental bulls.In Holstein bulls the age-dependent rise in plasma IGF-I was also found, whilst Holstein bulls had significantlylover IGF-I level, than Simmental bulls. The proportion of LL, VV and LV genotypes of GH in the randomlyselected herd of Simmental bulls was 0.25:0.20:0.55. Animals of VV genotype had lower body mass, daily gainand plasma IGF-I level, than bulls of LL and LV genotypes, whilst no differences in these indexes between LLand LV genotypes were found.  The observed association of growth rate, GH genotype and IGF-I level, suggest that GH genotype may affectmeat Performance via IGF-I secretion

Interrelationships between breed, growth hormone genotype, plasma IGF-I level and meat Performance in bulls of different ages (short communication)