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Asymptomatic infections and genetic diversity of Plasmodium falciparum play a major role in the natural acquisition of immunity to malaria. This study investigated the genetic diversity of msp1, msp2 and glurp in P. falciparum isolate from patients in Republic of Congo. The use of ACT selected different populations of P. falciparum between 2010 and 2018. This change in the parasites needs to be monitored to prevent a re-increase of malaria prevalence despite the use of ACT.

Temporal Changes in Genetic Diversity of Plasmodium Falciparum Populations in Isolates from Asymptomatic Children in Brazzaville after the Introduction of ACT