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During the course of their lifetime cells are exposed to different kinds of mechanical stress. These mechanical effects have a strong influence on a single cell, aggregated cells, their structure and metabolism especially in case of immunologic reaction similar to a chemical stimuli.Aim of this work is to introduce a modified electronic speckle pattern interferometry (ESPI) setup to this field of science to validate induced deformations in certain biological samples contact-free and thus close to their natural conditions.In the long term it is the aim to develop a “set” of these reference values and to use them in term of preliminary analysis for medical treatment.In conclusion this could lead to complete new approach in cell based analysis.

P1 - Induced cellular deformation as a standardized measurement method based on modified Micro-ESPI