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Fueled by their research and clinical diagnostics importance, chip-based methods for isolation and on-site analysis of blood components, such as plasma, red blood cells, white blood cells, extracellular vesicles (EV, e.g., exosomes, microvesicles), proteins, and circulating nucleic acids (cfDNA, miRNA) are developing rapidly. These challenges are compounded by the need to process diverse samples (whole blood, saliva, urine, cell cultures, water and food) across a large set of volumes (from l to few ml). The rapid, on-site, automated preparation from body fluids and molecular analysis of circulation biomarkers that have scientific and clinical value is critically important for timely decision making process and has not been addressed so far. This is particularly important for remote applications including low-resources communities or space research and medical support for long term space missions.

SM1.1 - Microfluidic-Based Platforms for Biological Assays Automation in Life-Sciences Research and Remote Medical Applications