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Patient 1: A 25-year-old woman was admitted with drop attack-like episodes that appeared after unexpected stimuli. She suffered from severe injuries because of frequent falls owing to stiff legs without the loss of consciousness and had insecure gait because of the fear of falling. She had freezing of gait while walking in wide halls but walked more comfortably in narrow corridors. She also had spasms on the lower limbs and emotional stress. Her legs were not stiff when she was a baby. During childhood, she was treated with carbamazepine and valproic acid cycles but achieved only partial clinical response. Although she discontinued medication during her pregnancy, she claimed that her complaints improved. Neurological examination was unremarkable, except for increased deep tendon reflexes.

Clinical and Electrophysiological Findings in Two Siblings with Familial Hyperekplexia