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There have been recent attempts to transfer well-established principles of rectal cancer management to colonic cancer, thereby offering neoadjuvant chemotherapy to high-risk patients at least in the trial settings. Traditionally, postoperative chemotherapy is offered to patients with colonic tumors that metastasize into regional lymph nodes and have features of extramural vascular invasion (EMVI). If the same criteria are used for the selection of patients with colonic cancer for neoadjuvant chemotherapy, then their accurate preoperative detection becomes of paramount importance. The aim of the study was to establish the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the computerized tomographic (CT) assessment of lymph node involvement and EMVI in colonic cancer.

Preoperative Computerized Tomographic Assessment of Regional Lymph Node and Extramural Vascular Invasion in Colonic Cancer